【中文名稱】：BRCA1 Polyclonal Antibody?
【英語名稱】：BRCA1 Polyclonal Antibody
【產(chǎn)品類型】：一抗
【中文名稱】：BRCA1 Polyclonal Antibody?
【英語名稱】：BRCA1 Polyclonal Antibody
【產(chǎn)品類型】：一抗
【供應(yīng)商】：Abbkine
【產(chǎn)品貨號(hào)】：ABP50789
【產(chǎn)品規(guī)格】：30ul/100ul/200ul
【背景資料】：BRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein(BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified
蛋白別名為：BRCA1; RNF53; Breast cancer type 1 susceptibility protein; RING finger protein 53;基因ID為：672；蛋白質(zhì)ID:P38398
【應(yīng)用類型】：WB，IHC-p，IF，ELISA
補(bǔ)充：*的抗體稀釋比例需要基于客戶實(shí)驗(yàn)進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
【免疫原】：合成多肽：human BRCA1 around the non-phosphorylation site of S1423.
【來源宿主】：兔
【反應(yīng)性】：人，大鼠
【保存建議】：廠家*藍(lán)冰運(yùn)輸.在發(fā)貨后能在-20℃保存1年.為zui大限度的避免損失，請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復(fù)凍融.
本產(chǎn)品為液體形式,溶解于PBS緩沖液中，含50%甘油，0.5%BSA和0.02%*.
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艾美捷科技有限公司品線覆蓋生物研究各個(gè)領(lǐng)域，主要包括：分子生物學(xué)（核酸蛋白研究工具、cDNA/RNA、轉(zhuǎn)染試劑、植物組培/細(xì)胞培養(yǎng)、生化試劑及試劑盒），試劑藥品（蛋白酶抑制劑、化合物、熒光染料/探針、動(dòng)物血清）、抗體（一抗、二抗、封閉血清）， 蛋白及試劑盒（細(xì)胞因子/重組蛋白、細(xì)胞凋亡/代謝/損傷、表觀遺傳、天然免疫）等。艾美捷為您尋找并提供*的產(chǎn)品解決方案、zui完備的物流服務(wù)、zui及時(shí)的售后服務(wù)。如果您對(duì)上述產(chǎn)品線感興趣，請(qǐng)致電免費(fèi)到艾美捷垂詢相關(guān)產(chǎn)品信息及完整實(shí)驗(yàn)解決方案。
產(chǎn)品標(biāo)簽:BRCA1 (phospho Ser1423) Polyclonal Antibody，BRCA1 Polyclonal Antibody
