“周期素依賴性激酶5抗體,Anti-CDK5抗體”應用于IHC、WB、 IF、IP、ELISA,質(zhì)量保證,無效免費退換,另外本公司生產(chǎn)經(jīng)營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑,咨詢!
產(chǎn)品介紹:
【產(chǎn)品名稱】:周期素依賴性激酶5抗體,Anti-CDK5抗體
【產(chǎn)品類型】:一抗
【產(chǎn)品編號】:BYk-0559R
【相關(guān)標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 狀】: Lyophilized or Liquid
【濃 度】: 1mg/1ml
【亞 型】: IgG
【規(guī) 格】:0.1ml/100ug,0.2ml/200ug
【抗體來源】: Rabbit OR MOUSE
【克隆類型】: polyclonal or monoclonal
【產(chǎn)品用途】:科研實驗,用于免疫組化實驗,WB實驗、IF、IP、ELISA實驗,相應的標記抗體有HRP標記抗體,F(xiàn)ITC標記,BIO等。
【貯 存】: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【詳細介紹】: CDK5 (Cyclin Dependent Kinase 5) is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression. CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
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