Anti-BRCA1抗體,乳腺癌易感基因1抗體產(chǎn)品詳細資料

產(chǎn)品編號 BYK-0803R

英文名稱 BRCA1
中文名稱 乳腺癌易感基因1抗體
別    名 BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; BRCA1_MOUSE; BRCAI; BRCC 1; BRCC1; Breast and ovarian cancer susceptibility protein 1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; PSCP; RING finger protein 53; RING finger protein 53; RNF53; BAP1.
研究領域 腫瘤  細胞生物  免疫學  染色質(zhì)和核信號  表觀遺傳學  
分 子 量 199kDa

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產(chǎn)品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產(chǎn)品應用不做依據(jù)，具體產(chǎn)品應用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-BRCA1抗體,乳腺癌易感基因1抗體產(chǎn)品介紹 

      This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. 

 此相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記 

     相關產(chǎn)品：

     Anti-GRO Alpha抗體,黑色素瘤刺激活性蛋白α抗體

Anti-Gastrin Releasing Peptide抗體,促胃泌素釋放肽抗體
Anti-GRP78抗體,葡萄糖調(diào)節(jié)蛋白78抗體
Anti-GRP94抗體,葡萄糖調(diào)節(jié)蛋白94抗體
Anti-GSK-3 Beta抗體,糖原合酶激酶3β抗體
Anti-GTP cyclohydrolase 1抗體,三磷酸鳥苷環(huán)水解酶抗體
Anti-GPR49抗體,G蛋白偶聯(lián)受體49抗體
Anti-Granulin抗體,顆粒蛋白前體抗體
Anti-Gemin 2抗體,運動神經(jīng)元存活蛋白結合蛋白1抗體
Anti-GDNF Receptor alpha 2抗體,膠質(zhì)細胞系源性神經(jīng)營養(yǎng)因子受體α2抗體
Anti-phospho-GSK-3 Beta(Ser9),磷酸化糖原合酶激酶3β抗體
Anti-galectin 9抗體,半乳糖凝集素9抗體
Anti-GLP-2抗體,胰高血糖素樣肽2抗體
Anti-GDF8抗體,生長分化因子8抗體
Anti-GABABR1抗體,gamma氨基丁酸B型受體1抗體
Anti-GABA B Receptor 2抗體,G氨基丁酸B型受體2抗體
Anti-GAD67抗體,*脫羧酶67抗體
Anti-GFP抗體,綠色熒光蛋白抗體
Anti-GM-CSF抗體,粒細胞-巨噬細胞克隆刺激因子抗體
Anti-gamma Synuclein抗體,核突觸蛋白γ抗體
Anti-Glutathione Reductase抗體,*還原酶抗體
Anti-GLP-1抗體,胰高血糖素樣肽1抗體