“CD74抗體，Anti-CD74/MHC II抗體”應(yīng)用于IHC、WB、 IF、IP、ELISA，質(zhì)量保證，無效免費退換，另外本公司生產(chǎn)經(jīng)營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！

產(chǎn)品介紹：

【產(chǎn)品名稱】：CD74抗體，Anti-CD74/MHC II抗體

【產(chǎn)品類型】：一抗

【產(chǎn)品編號】：BYk-2518R                    

【相關(guān)標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 狀】： Lyophilized or Liquid

【濃 度】： 1mg/1ml

【亞 型】： IgG

【規(guī) 格】：0.1ml/100ug，0.2ml/200ug

【抗體來源】： Rabbit OR MOUSE

【克隆類型】： polyclonal or monoclonal

【產(chǎn)品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應(yīng)的標記抗體有HRP標記抗體，F(xiàn)ITC標記，BIO等。

【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【詳細介紹】：CD74, also known as the MHC class II associated invariant chain （Ii）, is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of, or in association with, MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized. It has been proposed that cell surface CD74 binds MHC class II molecules which have lost their antigenic peptide leading to internalization and reloading with antigenic peptide. The transport route of class II alpha/beta/Ii complexes is regulated selectively by two forms of CD74 （p33 and p35） which are generated by the use of alternative translation initiation sites.
CD74 is expressed primarily by antigen presenting cells such as B lymphocytes （from before the pre-B cell stage to before the plasma cell stage）, macrophages and monocytes together, with many epithelial cells. CD74 may exist in different isoforms ranging in size from 33 to 41 kDa, depending on genetic splicing.
CD74抗體，Anti-CD74/MHC II抗體【相關(guān)產(chǎn)品】：
Anti-IL-4  白介素4抗體（大、小鼠）
Anti-IL-4  白介素4抗體（人）
Anti-IL-4R  白細胞介素4受體抗體
Anti-IL-5  白介素5抗體
Anti-IL-5Rα/CD125  白介素-5受體α鏈抗體
Anti-IL-6 Human  白介素6（人）
Anti-IL-6   白介素6抗體（大、小鼠）
Anti-IL-6   mouse rat  白介素6抗體
Anti-IL-7  白介素7抗體
Anti-IL-6Rα   白細胞介素6受體α抗體
Anti-IL6Rβ/CD130/gp130  白細胞介素6受體β抗體
Anti-IL-8/CXCL8  白介素8抗體
Anti-IL-8/CXCL8  白介素8抗體（大、小鼠）
Anti-IL-7Ra/CD127  白細胞介素-7受體a抗體
Anti-Mitofilin/IMMT  線粒體內(nèi)膜蛋白抗體
Anti-ILK-1   整合素連接激酶-1抗體
Anti-ILTV  抗雞傳染性喉氣管炎病毒抗體
Anti-ING1/p33  生長抑制因子基因1抗體
Anti-IMP3  胰島素樣生長因子ⅡmRNA結(jié)合蛋白3抗體
Anti-Inhibin α  抑制素α抗體
Anti-Inhibin beta A  抑制素beta A抗體
Anti-Inhibin beta B  抑制素βB抗體
Anti-Inhibin β C/Inhibin beta C  抑制素βC抗體
Anti-Insulin  胰島素抗體
Anti-Insulin Receptor-α  胰島素受體-α抗體