“肝細胞生長因子受體抗體,Anti-C-Met/Met/HGFR抗體”應用于IHC、WB、 IF、IP、ELISA，質(zhì)量保證，無效免費退換，另外本公司生產(chǎn)經(jīng)營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！

產(chǎn)品介紹：

【產(chǎn)品名稱】：肝細胞生長因子受體抗體,Anti-C-Met/Met/HGFR抗體

【產(chǎn)品類型】：一抗

【產(chǎn)品編號】：BYk-0668R                    

【相關標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 狀】： Lyophilized or Liquid

【濃 度】： 1mg/1ml

【亞 型】： IgG

【規(guī) 格】：0.1ml/100ug，0.2ml/200ug

【抗體來源】： Rabbit OR MOUSE

【克隆類型】： polyclonal or monoclonal

【產(chǎn)品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應的標記抗體有HRP標記抗體，F(xiàn)ITC標記，BIO等。

【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【詳細信息】： c-Met, a member of the tyrosine kinase superfamily, is the receptor for hepatocyte growth factor, also known as scatter factor （HGF/SF）. The mature c-Met protein is a disulfide-linked heterodimer with Mr=190 kDa composed of a heavily glycosylated alpha subunit that is compley extracellular in localization, and a beta subunit comprising an extracellular ligand binding domain, a single transmembrane domain, and a cytoplasmic tyrosine kinase domain. Cells expressing c-Met include epithelial cells, endothelial cells, blood cells of various types, and glomerular mesenchymal cells.
HGF/SF binding to c-Met stimulates receptor dimerization and the phosphorylation of numerous residues within the receptor’s cytoplasmic domain. Signaling proteins that are phosphorylated and/or localized in response to c-Met phosphorylation include: Grb2, Shc, Cbl, Crk, cortactin, paxillin, GAB1, PI3K, FAK, Src, Ras, ERK1 and 2, JNK, PLC gamma, AKT, and STAT3. HGF/SF stimulation of c-Met expressing cells enhances proliferation, migration, morphogenesis, and protease synthesis, characteristics that are associated with invasive cell phenotype. Many types of cancer exhibit sustained c-Met stimulation, overexpression, or mutation, including carcinomas of the colon, breast, ovary, lung, liver, prostate, thyroid, kidney, as well as melanomas and sarcomas. In addition to cancer studies, other research areas in which c-Met is under investigation include organogenesis, organ regeneration, angiogenesis and surgical wound healing.
  

肝細胞生長因子受體抗體,Anti-C-Met/Met/HGFR抗體【相關產(chǎn)品】：

Anti-phospho-ATF2(Thr51),磷酸化活化復制因子2抗體
Anti-ANAPC1抗體,細胞周期末期促進復合蛋白APC1抗體
Anti-phospho-APC1(Ser355),磷酸化細胞周期末期促進復合蛋白APC1抗體
Anti-phospho-APC1(Ser377),磷酸化細胞周期末期促進復合蛋白APC1抗體
Anti-ASAP1抗體,發(fā)育分化增強因子1抗體
Anti-phospho-ASAP1(Tyr782)抗體,磷酸化發(fā)育分化增強因子1抗體
Anti-AXL抗體,粘附相關激酶抗體
Anti-phospho-AQP2(Ser264),磷酸化水通道蛋白2抗體
Anti-phospho-AQP2(Ser269)抗體,磷酸化水通道蛋白2抗體
Anti-phospho-AKT1(Ser129),磷酸化蛋白激酶B抗體
Anti-phospho-ATF4(Ser245),磷酸化活化轉(zhuǎn)錄因子4抗體
Anti-phospho-Androgen Receptor(Ser213),磷酸化雄激素受體抗體
Anti-phospho-AKT1(Thr34)抗體,磷酸化蛋白激酶B抗體