Anti-CBP抗體,CREB結合蛋白抗體資料說明產(chǎn)品介紹：This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時4°C存儲，保質期六個月，*存儲時建議分裝為10ul以上小包裝-20°C存儲，并避免反復凍融，保質期一年。

產(chǎn)品名稱 Anti-CBP抗體,CREB結合蛋白抗體資料說明

產(chǎn)品編號 BYK-1397R

英文名稱 CBP
中文名稱 CREB結合蛋白抗體
別    名 CREB-binding protein; CREBBP; GTF2D; TATA binding factor; TATA box factor; TATA sequence binding protein; TBP; TFIID; Transcription initiation factor TFIID TBP subunit; GTF2D1; MGC117320; MGC126054; MGC126055; SCA 17; SCA17; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TBP; TF2D; TFIID; Transcription initiation factor TFIID TBP subunit; CBP/p300; CREB binding protein; Cyclic AMP-responsive enhancer binding protein; RSTS; RTS; Rubinstein-Taybi syndrome.
研究領域 細胞生物  神經(jīng)生物學  信號轉導  細胞凋亡  轉錄調節(jié)因子  激酶和磷酸酶                            

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應、產(chǎn)品應用 （具體交叉反應與產(chǎn)品應用請）

    Anti-CBP抗體,CREB結合蛋白抗體資料說明更多優(yōu)質產(chǎn)品有：

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