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變色酸 號(hào):148-25-4
英文名稱:Chromotropic acid;1,8-Dihydroxynaphthylene-3,6-disulfonic acid;4,5-Dihydroxynaphthalene-2,7-disulphonic acid
其他名稱:鉻變酸;1,8-二羥基萘-3,6-二磺酸;4,5-二羥基-2,7-萘二磺酸;比色酸
號(hào):148-25-4
C10H8O8S2=320.30
級(jí)別:CP
靈敏度試驗(yàn):合格
鹽酸溶解試驗(yàn):合格
性狀(以下信息僅供參考):白色或灰白色針狀結(jié)晶或粉末。接觸空氣易變色。實(shí)際商品常帶有色澤。溶于鹽酸和水
用途:本品僅供科研,不得用于其它用途。(以下用途僅供參考)鉻、鈦和甲醛的光度測(cè)定;鉻、鈦、酸鹽、甲醛、硝酸鹽和亞硝酸鹽的檢定;偶氮染料中間體
保存:RT,避光
客戶根據(jù)變色酸 號(hào):148-25-4性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號(hào)、沸點(diǎn)、熔點(diǎn)、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項(xiàng)、英文名、別稱、純度、級(jí)別等情況,本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定,運(yùn)輸條件不苛刻,一般儲(chǔ)存在陰涼,干燥,通風(fēng)良好的地方,遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
試劑品牌:TCI、sigma、Alfa、Avocado、Aldrich、ACROS、Fluka、ICN(MP)等
包裝:1kg、100g、10g、250g、25g、500g、50g、5g等包裝
級(jí)別:GR級(jí)別、AR級(jí)別、CP級(jí)別、L.P.級(jí)別等
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eventual recycling of the SNARE complex for subsequent membrane fusion (3,4).
Function : Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.
Subunit : Homohexamer. Interacts with GABARAP and GABARAPL2. Interacts with GRIA2. Interacts with PLK2, leading to disrupt the interaction with GRIA2. Interacts with MUSK; may regulate MUSK endocytosis and activity (By similarity). Interacts with CDK16 (By similarity).
Subcellular Location : Cytoplasm.
Post-translational modifications : Phosphorylation at Ser-569 interferes with homohexamerization (By similarity).
Similarity : Belongs to the AAA ATPase family.
Database links : UniProtKB/Swiss-Prot: P46459.3
英文名稱 Anti-Nephrin
中文名稱 腎小球細(xì)胞粘附分子受體抗體
別 名 CNF; Nephrin; Nephrosis 1 congenital Finnish type; Nephrosis 1, congenital, Finnish type (nephrin); NPHN; NPHN_HUMAN; NPHS 1; NPHS1; Renal glomerulus specific cell adhesion receptor; Renal glomerulus-specific cell adhesion receptor.
濃 度 1mg/1ml
規(guī) 格 0.1ml/100μg 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow
產(chǎn)品類型 一抗
變色酸 號(hào):148-25-4亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease. Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss. Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2. Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process. Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier. Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis. Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria. The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling.
Function : Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
Subunit : Interacts with CD2AP (via C-terminal domain). Interacts with MAGI1 (via PDZ 2 and 3 domains) forming a
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