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百里*號(hào)：125-20-2   
英文名稱：Thymolphthalein；Dithymolphthalide；5′,5″-Diisopropyl-2′,2″-dimethylphenolphth- alein；3,3-Bis(4-hydroxy-2-meth-yl-5-isopropylphenyl)phthalide    
其他名稱：百里香*；*酞；*麩    
號(hào)：125-20-2    
C28H30O4=430.54   
級(jí)別： IND   
熔點(diǎn)：251～255℃   
PH變色域：9.3（無色）～10.5（蘭色）   
乙醇溶解試驗(yàn)：合格   
氫氧化鈉溶解試驗(yàn)：合格   
灼燒殘?jiān)ㄒ粤蛩猁}計(jì)）：≤0.1%   
性狀(以下信息僅供參考)：白色或微黃色結(jié)晶性粉末。溶于醇和酮，溶于硫酸顯示紅色，溶于稀堿液顯示藍(lán)色，不溶于水   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)酸堿指示劑、檢驗(yàn)血液用試劑、色譜分析   
保存：RT 
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級(jí)別：GR級(jí)別、AR級(jí)別、CP級(jí)別、L.P.級(jí)別等
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room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Nur77 (also designated NGFI-B), Nurr1 (Nur-related factor 1), and NOR-1 (neuron-derived orphan receptor 1) constitute the NGFI-B subfamily within the nuclear receptor superfamily. Ligands for these protein have not been identified, and, therefore, they are designated “orphan nuclear receptors”. Genes of the NGFI-B subfamily are classified as immediate-early genes, which are induced rapidly, but transiently, in response to a variety of stimuli. They have been implicated in cell proliferation, differentiation, and apoptosis. The human NOR-1 gene maps to chromosome 9q, and encodes a protein which is expressed in heart, skeletal muscle, thymus, and spleen as well as in brain, where it is developmentally regulated. There-fore, NOR-1 may be involved in regulating neural differentiation. The NOR-1 gene also undergoes chromosomal translocation with the EWS gene to produce a protein thought to affect pre-mRNA splicing.
Function : Binds to the B1A response-element.
Subcellular Location : Nucleus.
Tissue Specificity : Isoform alpha is highly expressed in skeletal muscle. Isoform beta is highly expressed in skeletal muscle and low expressed in fetal brain and placenta.
DISEASE : Defects in NR4A3 are a cause of Ewing sarcoma (ES) [MIM:612219]. A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors. Note=A chromosomal aberration involving NR4A3 is found in patients with Erwing sarcoma. Translocation t(9;22)(q22-31;q11-12) with EWSR1. Note=A chromosomal aberration involving NR4A3 is a cause of a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with TAF2N.
百里*號(hào)：125-20-2Similarity : Belongs to the nuclear hormone receptor family. NR4 subfamily.
Contains 1 nuclear receptor DNA-binding domain.
Database links : UniProtKB/Swiss-Prot: Q92570.3
英文名稱  Anti-NOTUM
中文名稱  背板膠質(zhì)乙酰酯酶抗體
別    名  NOTUM; notum pectinacetylesterase homolog (Drosophila); Notum pectinacetylesterase homolog; NOTUM_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Cow, Horse, 54kDa 
產(chǎn)品類型  一抗   
研究領(lǐng)域  腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 
蛋白分子量  predicted molecular weight: 54kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NOTUM
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.