*號：518-47-8   
英文名稱：Fluorescein disodium salt；Uranine；Uranine yellow；Soluble fluorescein；Resorcinolphthalein sodium；C.I.45350    
其他名稱：螢光素鈉；熒光紅鈉；熒光黃鈉；熒光黃二鈉；熒光素二鈉；螢光橙紅鈉；螢光素二鈉；9-(鄰羧基苯基)-6-羥基-3H-呫噸-3-酮二鈉鹽    
號：518-47-8    
C20H10O5Na2=376.27   
級別：BS   
pH（10g/L，25℃）：7.0～8.5    
干燥失重：≤7.0%    
生物染色試驗：合格   
水溶解試驗：合格   
性狀(以下信息僅供參考)：橙紅色粉末。無氣味。有吸濕性。易溶于水，溶液呈黃紅色，并帶*的黃綠色熒光，酸化后消失，中和或堿化后又出現(xiàn)，微溶于乙醇，幾乎不溶于方和乙迷。水溶液與血漿等滲。Z大吸收波長(水)493.5mm。   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)吸附指示劑；氧化還原指示劑。熒光光度分析硫離子；滴定、溴和碘   
保存：RT *號：518-47-8儲存條件：
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產(chǎn)品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸：汽車運輸、EMS郵政快遞，申通快遞等， 款到上海3天內發(fā)貨；
售后：如您對我們的產(chǎn)品服務及技術指標有特殊要求，請及時通知我方。
存儲：應貯存在干燥清潔避光的環(huán)境中，嚴禁與有毒物質混放，以免污染（保質期為兩年）。
*號：518-47-8主要優(yōu)級純、分級純和化學純3種：
（1）優(yōu)級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質含量Z低，適合于重要精密的分析工作和科學研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優(yōu)級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學校一般分析工作。使用藍色（深藍色）標簽。
（4）實驗試劑（LR：Laboratory reagent），又稱四級試劑。
服務承諾：
工作時間內提供免費的技術咨詢和指導 。我公司的銷售工程師經(jīng)過專業(yè)培訓的，將為您提供滿意的產(chǎn)品和真誠的服務。
Phosphorylated. Phosphorylation may be mediated by CDK2.
Autosumoylated.
DISEASE : Note=Associated with various cancers. DNA copy number loss is found in multiple kinds of malignancies originating from the brain, breast, stomach, kidney, hematopoietic tissue and lung.
Similarity : Contains 1 PHD-type zinc finger.
Contains 1 RING-type zinc finger.
Contains 1 ubiquitin-like domain.
Contains 1 YDG domain.
Database links : UniProtKB/Swiss-Prot: Q96PU4.1
英文名稱  Anti-NEK8
中文名稱  */*蛋白激酶NEK8抗體
別    名  JCK; NEK 8; NEK12A; NEK8; NEK8_HUMAN; Never in mitosis A-related kinase 8; NIMA-family kinase NEK8; NIMA-related kinase 12a; Nima-related protein kinase 12a; NimA-related protein kinase 8; Serine/threonine-protein kinase Nek8.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human, Mouse, Rat, Chicken, Dog, Cow
產(chǎn)品類型  一抗   
研究領域  細胞生物 細胞周期蛋白 激酶和磷酸酶 表觀遺傳學 
蛋白分子量  predicted molecular weight: 75kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NEK8
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Required for renal tubular integrity.
Tissue specificity: Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma.
Function : Required for renal tubular integrity. May regulate localcytoskeletal structure in kidney tubule epithelial cells. Mayregulate ciliary biogenesis through targeting of proteins to thecilia (By similarity).
Subunit : Interacts with PKD2; may regulate PKD2 targeting to thecilium (By similarity).
Subcellular Location : Cytoplasm (By similarity). Cytoplasm,cytoskeleton. Cell projection, cilium (By similarity).Note=Predominantly cytoplasmic. Localizes to the proximal region ofthe primary cilium and is not observed in dividing cells.
Tissue Specificity : Highest expression in thyroid, adrenal glandand skin. Low levels in spleen, colon and uterus. Overexpressed inbreast tumors, with highest expression in infiltrating ductalcarcinomas and moderate levels in mucinous adenocarcinoma.
DISEASE : Defects in NEK8 are the cause of nephronophthisis type 9(NPHP9) [MIM:613824]. NPHP9 is an autosomal recessive disorderresulting in end-stage renal disease. It is a progressivetubulo-interstitial kidney disorder histologically characterized bymodifications of the tubules with thickening of the basementmembrane, interstitial fibrosis and, in the advanced stages,medullary cysts.
Similarity : Belongs to the protein kinase superfamily. NEK Ser/Thrprotein kinase family. NIMA subfamily.
Contains 1 protein kinase domain.