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N-(4-氨基丁基)-N-乙基異魯米諾號:66612-29-1
3,3'5,5'-四甲基聯苯胺丙磺酸鈉號:102062-36-2
N-乙基-N-(3-磺丙基)-3-甲氧基苯胺鈉鹽號:82611-88-
鈣鎂試劑號:3147-14-6
英文名稱:Calmagite;1-(1-Hydroxy-4-methyl-2-phenylazo)-2-naphthol-4-sulfonic acid;3-Hydroxy-4-(2-hydroxy-5-methylphenylazo)naphthalene-1-sulfonic acid
其他名稱:3-羥基-4-[(2-羥基-5-甲基苯基)偶氮]-1-萘磺酸;1-(1-羥基-4-甲基-2-苯偶氮)-2-萘酚-4-磺酸;鈣鎂指示劑
號:3147-14-6
C17H14N2O5S=358.37
級別:IND
熔點:≥330℃
UV absorption:λmax 605~615nm
性狀(以下信息僅供參考):暗褐色或黑色結晶粉末,不溶于水
用途:本品僅供科研,不得用于其它用途。(以下用途僅供參考)在用EDTA滴定Ca、Mg金屬離子時作為指示劑
保存:RT 鈣鎂試劑號:3147-14-6儲存條件:
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋!受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
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存儲:應貯存在干燥清潔避光的環(huán)境中,嚴禁與有毒物質混放,以免污染(保質期為兩年)。
鈣鎂試劑號:3147-14-6主要優(yōu)級純、分級純和化學純3種:
(1)優(yōu)級純(GR:Guaranteed reagent),又稱一級品或保證試劑,99.8%,這種試劑純度Z高,雜質含量Z低,適合于重要精密的分析工作和科學研究工作,使用綠色瓶簽。
(2)分析純(AR),又稱二級試劑,純度很高,99.7%,略次于優(yōu)級純,適合于重要分析及一般研究工作,使用紅色瓶簽。
(3)化學純(CP),又稱三級試劑,≥ 99.5%,純度與分析純相差較大,適用于工礦、學校一般分析工作。使用藍色(深藍色)標簽。
(4)實驗試劑(LR:Laboratory reagent),又稱四級試劑。
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in many cranial ganglia, the ophtalmic nerve, the vestibular system, multiple facial structures, the submaxillary glands, and dorsal root ganglia. Isoform TrkB-T1 is mainly expressed in the brain but also detected in other tissues including pancreas, kidney and heart. Isoform TrkB-T-Shc is predominantly expressed in the brain.
Post-translational modifications : Phosphorylated. Undergoes ligand-mediated autophosphorylation that is required for interaction with SHC1 and PLCG1 and other downstream effectors. Isoform TrkB-T-Shc is not phosphorylated.
Ubiquitinated. Undergoes polyubiquitination upon activation; regulated by NGFR. Ubiquitination regulates the internalization of the receptor (By similarity).
DISEASE : Defects in NTRK2 are the cause of obesity hyperphagia and developmental delay (OHPDD) [MIM:613886]. OHPDD is a disorder characterized by early-onset obesity, hyperphagia, and severe developmental delay in motor function, speech, and language.
Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.
Contains 1 protein kinase domain.
Database links : UniProtKB/Swiss-Prot: Q16620.1
NGF, BDNF, NT-3, NT-4等的受體包括trkA, trkB, trkC及NGFR。BDNF, NT-3能誘導trkB的*磷酸化(神經生長因子受體的一種)。此抗體與Trk C同源。
英文名稱 Anti-phospho-TrkB (Tyr705)
中文名稱 磷酸化*激酶B抗體
別 名 TrkB (Phospho-Tyr705); phospho-NTRK2(Tyr705); NTRK2(phospho Y705); TrkB; Tyrosine Receptor Kinase B; Tyrosine kinase,Pyk2; BDNF tropomyosine receptor kinase B; BDNF/NT 3 growth factors receptor; BDNF/NT-3 growth factors receptor; Brain derived neurotrophic factor receptor; GP145 TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic tyrosine kinase receptor type 2; Neurotrophin receptor tyrosine kinase type 2; NTRK 2; Ntrk2; NTRK2_HUMAN; Obesity, hyperphagia, and developmental delay, included; RATTRKB1; Tkrb; Trk B; Trk-B; TRKB; TrkB tyrosine kinase; TRKB1; tyrosine kinase receptor B; Tyrosine receptor kinase B.
濃 度 1mg/1ml
規(guī) 格 0.1ml/100μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
產品類型 一抗 磷酸化抗體
研究領域 免疫學 神經生物學 信號轉導 轉錄調節(jié)因子 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 92kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from rat NTRK2 around the phosphorylation site of Tyr705
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應用 WB=1:100-500 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
鈣鎂試劑號:3147-14-6not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or
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