ABTS底物片劑號：30931-67-0   
英文名稱：ABTS substrate tablets   
其他名稱：2,2′-聯(lián)氨-雙（3-乙基苯并噻唑啉-6-磺酸）二胺鹽底物；2,2’-連氮基-雙-(3-乙基苯并二氫噻唑啉-6-磺酸)二銨鹽底物；2,2'-二氮-雙(3-乙基苯并噻唑-6-磺酸)銨鹽底物   
號：30931-67-0   
C18H24N6O6S4=548.68   
級別：試劑級   
總重量：138～142mg   
λmax(1Tab/100ml)：336～346nm   
性狀(以下信息僅供參考)：片劑。Each tablets contain 10mg of ABTS for quick and easy preparation of substrate solution.   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)The product is supplied as a ready-to-use peroxidase substrate containing 2,2-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) in an acidic buffer.The substrate should be colorless prior to reaction with peroxidase.It will develop a blue-green reaction product when reacted with peroxidase in microwell applications(e.g.ELISA assays).For end-point assays,1% sodium dodecyl sulfate(SDS) may be used to stop the reaction.This will also result in a blue-green end product.Since this substrate produces a soluble reaction produet,it is not recommended for blotting or histochemical applications.   
保存：-20℃

ABTS底物片劑號：30931-67-0儲存條件：
避光、干燥陰涼處封閉貯存,嚴(yán)禁與有毒、有害物品混放、混運(yùn)。本品為非危險(xiǎn) 產(chǎn)品可按一般化學(xué)品運(yùn)輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運(yùn)輸條件比較苛刻。
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存儲：應(yīng)貯存在干燥清潔避光的環(huán)境中，嚴(yán)禁與有毒物質(zhì)混放，以免污染（保質(zhì)期為兩年）。
ABTS底物片劑號：30931-67-0主要優(yōu)級純、分級純和化學(xué)純3種：
（1）優(yōu)級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質(zhì)含量Z低，適合于重要精密的分析工作和科學(xué)研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優(yōu)級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學(xué)純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學(xué)校一般分析工作。使用藍(lán)色（深藍(lán)色）標(biāo)簽。
（4）實(shí)驗(yàn)試劑（LR：Laboratory reagent），又稱四級試劑。
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Subunit : Interacts with YWHAE. Interacts directly with NEFL and indirectly with NEFH. Interacts with microtubules (By similarity). Self-associates. Interacts with DISC1, dynein, dynactin, tubulin gamma, KATNA1, KATNB1, PAFAH1B1, PCM1 and PCNT. Interacts (via C-terminus) with CENPF. Interacts with ZNF365.
Subcellular Location : Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the cell body of the motor neurons and colocalizes with assembled neurofilaments within axonal processes. Localizes to the microtubules of the manchette in elongated spermatids. Colocalizes with DISC1 in the perinuclear region, including the centrosome (By similarity). Localizes to the interphase centrosome and the mitotic spindle. Localizes to the kinetochore in a CENPF-dependent manner.
Tissue Specificity : Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Post-translational modifications : Phosphorylated in mitosis. Can be phosphorylated by CDK1, CDK5 and MAPK1. Phosphorylation by CDK5 promotes interaction with KATNA1 and YWHAE.
Palmitoylation at Cys-273 reduces affinity for dynein.
Similarity : Belongs to the nudE family.
Database links : UniProtKB/Swiss-Prot: Q9GZM8.1
中心粒蛋白Nudel是動物細(xì)胞中，中心體微管組織的主要細(xì)胞器，是細(xì)胞質(zhì)動力蛋白調(diào)節(jié)因子在中心體組裝及徽管組織中發(fā)揮重要作用。
英文名稱  Anti-NEURL/RNF67
中文名稱  環(huán)指蛋白67抗體
別    名  h neu; h neuralized 1; Neuralized homolog; Neuralized like protein 1; NEURL1; RING finger protein 67; RNF67; NEU1A_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep
產(chǎn)品類型  一抗   
研究領(lǐng)域  細(xì)胞生物 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 
蛋白分子量  predicted molecular weight: 62kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NEURL/RNF67
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is ABTS底物片劑號：30931-67-0stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors.
Function : May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway
Subcellular Location : Cell membrane; Peripheral membrane protein (By similarity). Cytoplasm, perinuclear region.
Tissue Specificity : Expressed in brain, testis, pituitary gland, pancreas and bone marrow. Also poorly expressed in an malignant astrocytomas and several neuroectodermal tumor cell lines.