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磷鎢酸號(hào)：12501-23-4   
英文名稱(chēng)：Phosphotungstic acid hydrate；Tungstophosphoric acid hydrate；Dodecatungstophosphoric acid hydrate   
其他名稱(chēng)：磷鎢酸水合物；鎢磷酸水合物；12-鎢磷酸水合物   
號(hào)：12501-23-4   
H3[P(W3O10)4] · xH2O=2880.05 (anhydrous basis)   
級(jí)別：AR   
澄清度試驗(yàn)：合格   
重金屬(以Pb計(jì))：≤0.002%   
化物：≤0.03%   
銨鹽：≤0.02%   
硫酸鹽：≤0.02%   
鐵：≤0.002%   
水不溶物：≤0.02%   
鈉：≤0.02%   
鈣：≤0.02%   
硝酸鹽：≤0.01%   
性狀(以下信息僅供參考)：白色或微帶黃綠色結(jié)晶或結(jié)晶性粉末。略有風(fēng)化性。溶于約0.5份水，溶于乙醇、乙迷   
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sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation.
Function : Plays a key role in the sexual differentiation of germcells by promoting the male fate but suppressing the female fate.Represses the female fate pathways by suppressing meiosis, which inturn results in the promotion of the male fate. Maintains thesuppression of meiosis by preventing STRA8 expression, which isrequired for premeiotic DNA replication, after CYP26B1 isdecreased. Regulates the localization of the CCR4-NOT deadenylationcomplex to P-bodies and plays a role in recruiting the complex totrigger the degradation of mRNAs involved in meiosis. Required forthe maintenance of the spermatogonial stem cell population. Notessential for the assembly of P-bodies but is required for themaintenance of their normal state (By similarity).
Subunit : Interacts with C, CNOT3, CNOT6L, CNOT7 and CNOT9 (Bysimilarity).
Subcellular Location : Cytoplasm. Cytoplasm, P-body (Bysimilarity). Cytoplasm, perinuclear region. Note=Localizes atP-bodies during gonocyte development (By similarity). More abundantin perinuclear region of the cytoplasm of the germ cells of theadult testis.
Tissue Specificity : Testis and ovary. Expression found in severalspermatogenic stages: in cells on the periphery of the tubuleswhich could correspond to spermatogonia, in spermatocytes and inround spermatids (at protein level).
Similarity : Belongs to the nanos family.
Contains 1 nanos-type zinc finger.
Database links : UniProtKB/Swiss-Prot: P60321.1
英文名稱(chēng)  Anti-NUP54
中文名稱(chēng)  NUP54抗體
別    名  54 kDa nucleoporin; MGC13407; Nucleoporin p54; NUP54_HUMAN.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來(lái)源  Rabbit 
克隆類(lèi)型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit
產(chǎn)品類(lèi)型  一抗   
研究領(lǐng)域  腫瘤 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 
蛋白分子量  predicted molecular weight: 55kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NUP54
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.