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2-脫氧-2-氟-D-葡萄糖號:29702-43-0
英文名稱:FDG;2-Fluoro-2-deoxy-D-glucose
其他名稱:氟代脫氧葡萄糖;2-氟-2-脫氧-D-葡萄糖;氟-[18F]脫氧葡萄糖
號:29702-43-0
C6H11FO5=182.15
級別:BR
純度:≥98%
性狀(以下信息僅供參考):白色或黃色粉末,溶于水:49mg/ml
用途:本品僅供科研,不得用于其它用途
保存:2~8℃2-脫氧-2-氟-D-葡萄糖號:29702-43-0儲存條件:
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產(chǎn)品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋!受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸:汽車運輸、EMS郵政快遞,申通快遞等, 款到上海3天內(nèi)發(fā)貨;
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存儲:應貯存在干燥清潔避光的環(huán)境中,嚴禁與有毒物質(zhì)混放,以免污染(保質(zhì)期為兩年)。
2-脫氧-2-氟-D-葡萄糖號:29702-43-0主要優(yōu)級純、分級純和化學純3種:
(1)優(yōu)級純(GR:Guaranteed reagent),又稱一級品或保證試劑,99.8%,這種試劑純度Z高,雜質(zhì)含量Z低,適合于重要精密的分析工作和科學研究工作,使用綠色瓶簽。
(2)分析純(AR),又稱二級試劑,純度很高,99.7%,略次于優(yōu)級純,適合于重要分析及一般研究工作,使用紅色瓶簽。
(3)化學純(CP),又稱三級試劑,≥ 99.5%,純度與分析純相差較大,適用于工礦、學校一般分析工作。使用藍色(深藍色)標簽。
(4)實驗試劑(LR:Laboratory reagent),又稱四級試劑。
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The Six proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six2, Six4 (AREC3) and Six5 bind to the same DNA sequence, indicating that they may regulate the same target genes. Six1 and Six4 are both capable of transactivating MEF3 site containing reporter genes, such as myogenin. It has been demonstrated that alterations to homeobox-containing genes may result in cancer. Six1 expression has been shown to be absent or low in normal adult tissues, although it is expressed in several tumor types, including breast carcinoma. Six1 overexpression has been shown to abrogate the G2 cell cycle checkpoint. Six2 is highly expressed in fetal tissues but expression is limited in adult tissues.
Function : May be involved in limb tendon and ligament development.
Subcellular Location : Nucleus.
Tissue Specificity : Strongly expressed in skeletal muscle.
Similarity : Belongs to the SIX/Sine oculis homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links : UniProtKB/Swiss-Prot: Q9NPC8.1
英文名稱 Anti-SUMF1
中文名稱 硫酸酯酶修飾因子1抗體
別 名 MGC150436; AAPA3037; C alpha formylglycine generating enzyme 1; C-alpha-formylglycine-generating enzyme 1; FGE; FGly generating enzyme; MGC131853; Sulfatase modifying factor 1 [Precursor]; Sulfatase-modifying factor 1; SUMF1; SUMF1_HUMAN; UNQ3037.
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
產(chǎn)品類型 一抗
2-脫氧-2-氟-D-葡萄糖號:29702-43-0研究領域 細胞生物 發(fā)育生物學 神經(jīng)生物學 信號轉(zhuǎn)導 干細胞
蛋白分子量 predicted molecular weight: 37kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SUMF1
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.
Function : Using molecular oxygen and an unidentified reducing agent, oxidizes a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also called C(alpha)-formylglycine. Known substrates include GALNS, ARSA, STS and ARSE.
Subunit : Monomer, homodimer and heterodimer with SUMF2.
Subcellular Location : Endoplasmic reticulum lumen.
Tissue Specificity : Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart.
Post-translational modifications : N-glycosylated. Contains high-mannose-type oligosaccharides.
DISEASE : Defects in SUMF1 are the cause of multiple sulfatase deficiency (MSD) [MIM:272200]. MSD is a clinically and biochemically heterogeneous disorder caused by the simultaneous impairment of all sulfatases, due to defective post-translational modification and activation. It combines features of individual sulfatase deficiencies such as metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay. Inheritance is autosomal recessive.
Similarity : Belongs to the sulfatase-modifying factor family.
Database links : UniProtKB/Swiss-Prot: Q8NBK3.3
英文名稱 Anti-STK33
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