Reagent: in vivo-jetRNA®+ transfection reagent(polyplus RNA脂質(zhì)體轉(zhuǎn)染試劑).

Molecule delivered: mRNA.

Applications: Vaccination / immunization;

Cancer therapy;

in vivo functional studies (Gene expression, CRISPR genome editing).

Targeted organs: All organs (depending on the injection route).

Injection routes: Various administration routes (systemic or local);

Intravenous / intramuscular / intraperitoneal and retro-orbital injections have been successfully tested.

Number of injections in mice: 1 mL is sufficient to perform at least 50 intravenous injections or 100 intramuscular injections in mice.

Storage: Store in vivo-jetRNA®+ at 5 °C ± 3°C. Do not freeze.

Provided with: mRNA buffer.

Highlights:

·Efficient: 100% mRNA encapsulation leading to comparable LNP delivery results;

·Time saving: Ready-to-use reagent that does not require formulation equipment;

·Stable: Maintain liposome size using low to high mRNA concentration over time;

·Universal: Target any organ/tissue using various administration routes;

·Safe: Maintain healthy animals and organs.