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Anti-IL-1抗體供應(yīng)商

From：Abcam

Catalog Number : BYK-51035R      
Quantity size :   0.1ml  (1mg/ml,Lyophilized or Liquid.Buffer=0.01M PBS,ph 7.4 with 10 mg/ml BSA and 0.1% Sodium azide.Reconstitute with 0.1ml sterile distilled water.)

background: IL-1(Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors,NFκB and AP-1,thereby promoting host response to injury or infection.The IL-1superfamily is comprised of several ligands and receptors. IL-1F5,also know as IL-1δ,IL-1 like protein 1(IL-1L1),IL-1HY1,IL-1ra(receptor antagonist) homolog 1 or IL-1 ralated protein 3(IL-1rp3), is a secreted ligand belong to this superfamily.IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similary lacks the loop between the fourth and fifth β-strands. IL-1Fcts as an antagonist, inhibiting the IL-1F9 activation of NFκB. Similar to other family members, IL-1F5 can be regulated by bacterial lipopolysaccharide(LPS).

Specificity :   

• Anti-IL-1 is a rabbit Polyclonal antibody unconjugated                
• specific for IL-1 of Human, Mouse, Rat, 
• use for western blotting,elisa,immunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification, purity :>95%
• Isotype:  IgG
• mol wt:  17kDa

Application :  

• Western blotting=1:100-500                
• Immunohistocry 1:100-500                
• ELISA= 1:500-1000  
• IHC-P=1:100-500  IHC-F=1:100-500

Optimal working dilutions must be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.